Tramadol with Paracetamol: Informations of Tramadol with Paracetamol

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Tramadol is a narcotic-like pain reliever. Tramadol is used to treat moderate to severe pain. Tramadol is regularly used in the form of an ingredient in multi-agent topical gels, creams, and solutions for nerve pain, rectal foam, concentrated retention enema, and a skin plaster quite similar to those used with lidocaine. Tramadol belongs to the class of drugs known as opiate agonists. Tramadol with Paracetamol works by changing the way the body senses pain. Tramadol with Paracetamol may be prescribed as an immediate release tablet (50 mg.) or as an extended release tablet (100, 200, or 300 mg.). The extended release tablets are usually reserved for patients with chronic pain who require continuous, long-term treatment. Tramadol extended release tablets must be taken whole, not split, chewed or crushed.

Paracetamol is one of the most common drugs used in the world, and is manufactured in huge quantities. The starting material for the commercial manufacture of paracetamol is phenol, which is nitrated to give a mixture of the ortho and para-nitrotoluene. The o-isomer is removed by steam distillation, and the p-nitro group reduced to a p-amino group. This is then acetylated to give paracetamol. Tramadol with Paracetamol is a potent drug that is available without prescription, it is often used in suicide attempts, and in this respect it is potentially more dangerous than other over-the-counter drugs such as aspirin. This is because paracetamol overdoses often cause liver failure, and there have been many cases where attempted suicides have awakened from an overdose and changed their minds, yet still died a few days later from liver damage.